Patent · US Active

Methods and compositions for the specific inhibition of transthyretin (TTR) by double-stranded RNA

US10150965B2 · kind B2 · utility

5Cited by

2References

24Claims

0Family size

Assignee

Dicerna Pharmaceuticals, Inc. · US

Inventors

Bob D. Brown · Littleton, US
Henryk T. Dudek · Wellesley, US

Key dates

Filing date	Dec 5, 2014
Grant date	Dec 11, 2018
Priority date	—
Expiry date	Dec 5, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/178
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention relates to compounds, compositions, and methods useful for reducing transthyretin (TTR) target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate siRNA (DsiRNA) agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.