Lipid probes and uses thereof

US10168342B2 · kind B2 · utility

Assignee

• THE SCRIPPS RESEARCH INSTITUTE · US

Inventors

• Benjamin F. Cravatt · San Diego, US
• Micah J. Niphakis · San Diego, US
• Kenneth M. Lum · San Diego, US
• Bruno Correia · San Diego, US
• Armand Cognetta · San Diego, US
• Jonathan Hulce · Libertyville, US

Key dates

• Filing date: Mar 25, 2016
• Grant date: Jan 1, 2019
• Expiry date: Mar 25, 2036

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2570/00
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Disclosed herein are methods, compositions, probes, assays and kits for identifying a lipid binding protein as a drug binding target. Also disclosed herein are methods, compositions, and probes for mapping a ligand binding site on a lipid binding protein, identification of lipid binding proteins, generating drug-lipid binding protein profiles, high throughput drug screening, and identification of drugs as potential lipid binding protein ligands.