Patent assignee · US · UNIVERSITY

THE SCRIPPS RESEARCH INSTITUTE

1,203Patents
575Active
1,203Granted
56Portfolio score

Filing activity: Jun 25, 1987 → Jun 5, 2024 · 159 expiring within 5 years

Most-cited patents

PatentTitleAreaCited byStatus
US5658727A Heterodimeric receptor libraries using phagemids Chemistry; Metallurgy 633 Expired
US6140081A Zinc finger binding domains for GNN Chemistry; Metallurgy 367 Expired
US6140466A Zinc finger protein derivatives and methods therefor Chemistry; Metallurgy 314 Expired
US6242568A Zinc finger protein derivatives and methods therefor Chemistry; Metallurgy 305 Expired
US5573905A Encoded combinatorial chemical libraries Chemistry; Metallurgy 299 Expired
US5959177A Transgenic plants expressing assembled secretory antibodies Chemistry; Metallurgy 289 Expired
US6440710B1 Antibody-catalyzed deuteration, tritiation, dedeuteration or detritiation of carbonyl compounds Chemistry; Metallurgy 286 Expired
US7045337B2 In vivo incorporation of unnatural amino acids Chemistry; Metallurgy 285 Expired
US7087409B2 Humanization of murine antibody Chemistry; Metallurgy 283 Expired
US6060596A Encoded combinatorial chemical libraries Chemistry; Metallurgy 273 Expired
US6417429B1 Transgenic plants expressing assembled secretory antibodies Chemistry; Metallurgy 245 Expired
US7375234B2 Copper-catalysed ligation of azides and acetylenes Performing Operations; Transporting 245 Expired
US7083970B2 Methods and compositions for the production of orthogonal tRNA-aminoacyl tRNA synthetase pairs Chemistry; Metallurgy 218 Expired
US6326174A Enzymatic DNA molecules Chemistry; Metallurgy 179 Expired
US6291158A Method for tapping the immunological repertoire Chemistry; Metallurgy 167 Expired
US5877289A Tissue factor compositions and ligands for the specific coagulation of vasculature Chemistry; Metallurgy 160 Expired
US6927042B2 Glycoprotein synthesis Chemistry; Metallurgy 155 Expired
US5264586A Analogs of calicheamicin gamma1I, method of making and using the same Chemistry; Metallurgy 141 Expired
US5374541A Combined use of .beta.-galactosidase and sialyltransferase coupled with in situ regeneration of CMP-sialic acid for one pot synthesis of oligosaccharides Chemistry; Metallurgy 132 Expired
US5667988A Methods for producing antibody libraries using universal or randomized immunoglobulin light chains Chemistry; Metallurgy 126 Expired
US6184344A Synthesis of proteins by native chemical ligation Chemistry; Metallurgy 121 Expired
US6004555A Methods for the specific coagulation of vasculature Chemistry; Metallurgy 118 Expired
US6096551A Methods for producing antibody libraries using universal or randomized immunoglobulin light chains Chemistry; Metallurgy 99 Expired
US6903189B2 Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis Human Necessities 95 Expired
US7273844B2 Tryptophanyl-tRNA synthetase-derived polypeptides useful for the regulation of angiogenesis Emerging Cross-Sectional Technologies 94 Expired

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.