Papillomavirus pseudoviruses for detection and therapy of tumors

US10188751B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Secretary, Department of Health and Human Services · US

Inventors

• Jeffrey Roberts · Rockville, US
• Douglas R. Lowy · Washington, US
• John T. Schiller · Silver Spring, US

Key dates

• Filing date: Dec 2, 2014
• Grant date: Jan 29, 2019
• Expiry date: Apr 18, 2035

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/025
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are methods of detecting tumors, monitoring cancer therapy, and selectively inhibiting the proliferation and/or killing of cancer cells utilizing a papilloma pseudovirus or a papilloma virus-like particle (VLP).