Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection

US10189838B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Lisha Wang · Basel, CH
• Lu Gao · Shanghai, CN
• Mengwei Huang · Shanghai, CN
• Lei Guo · Kowloon, CN
• Chungen Liang · Shanghai, CN
• Wei Zhu · Shanghai, CN
• Song Feng · Shanghai, CN
• Xiufang Zheng · Shanghai, CN
• Weixing Zhang · Shanghai, CN
• Guolong Wu · Shanghai, CN
• Baoxia Wang · Shanghai, CN
• Hongying Yun · Shanghai, CN

Key dates

• Filing date: Nov 16, 2015
• Grant date: Jan 29, 2019
• Expiry date: Nov 16, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, R5, R6, W1, W2, W3, A and X are as described herein, compositions including the compounds and methods of using the compounds for the treatment and prophylaxis of respiratory syncytial virus infection.