Method of culturing eukaryotic cells
US10190084B2 · kind B2 · utility
3Cited by
5References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 8, 2014 |
| Grant date | Jan 29, 2019 |
| Priority date | — |
| Expiry date | Sep 8, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2500/05
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An apparatus and method to maintain pH within a range conducive for cell growth in a bicarbonate-containing cell culture system without the addition of base. The method relies on the gas transfer characteristics of the bioreactor system to modulate the CO2 transfer to and from the cell culture such that the pH of the cell culture can be maintained within a desired range.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.