Biomarkers for detecting pre-cachexia or cachexia and methods of treatment thereof
US10191033B2 · kind B2 · utility
1Cited by
1References
11Claims
0Family size
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Key dates
| Filing date | Dec 4, 2014 |
| Grant date | Jan 29, 2019 |
| Priority date | — |
| Expiry date | Dec 4, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/60
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides markers indicative of pre-cachexia, compositions and methods for identifying patients with a molecular signature indicative of pre-cachexia; a culture system that reproduces the cachetic process in cells in vitro, which facilitates the screening and identification of therapeutic agents useful for disrupting (slowing, reducing, reversing, or preventing) the progression of pre-cachexia to refractory cachexia; as well as therapeutic agents identified using the culture system of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.