Cytotoxic and anti-mitotic compounds, and methods of using the same
US10201614B2 · kind B2 · utility
3Cited by
31References
38Claims
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Assignee
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Key dates
| Filing date | Mar 14, 2014 |
| Grant date | Feb 12, 2019 |
| Priority date | — |
| Expiry date | Mar 14, 2034 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds having cytotoxic and/or anti-mitotic activity are disclosed. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. Also disclosed are compositions having the structure: (T)-(L)-D), wherein (T) is a targeting moiety, (L) is an optional linker, and (D) is a compound having cytotoxic and/or anti-mitotic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.