Patent assignee · CA · COMPANY

ZYMEWORKS INC.

56Patents
56Active
56Granted
55Portfolio score

Filing activity: May 26, 2006 → Oct 7, 2019 · 2 expiring within 5 years

Most-cited patents

PatentTitleAreaCited byStatus
US9562109B2 Stable heterodimeric antibody design with mutations in the Fc domain Chemistry; Metallurgy 63 Active
US9574010B2 Stable heterodimeric antibody design with mutations in the Fc domain Chemistry; Metallurgy 37 Active
US9499634B2 Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells Chemistry; Metallurgy 36 Active
US9522876B2 Cytotoxic and anti-mitotic compounds, and methods of using the same Emerging Cross-Sectional Technologies 18 Active
US10000576B1 Bispecific antigen-binding constructs targeting HER2 Chemistry; Metallurgy 18 Active
US9388231B2 Multivalent heteromultimer scaffold design and constructs Chemistry; Metallurgy 15 Active
US9499605B2 Multivalent heteromultimer scaffold design and constructs Chemistry; Metallurgy 15 Active
US9914785B2 Engineered immunoglobulin heavy chain-light chain pairs and uses thereof Chemistry; Metallurgy 12 Active
US9879086B2 Cytotoxic and anti-mitotic compounds, and methods of using the same Electricity 11 Active
US10077298B2 Engineered immunoglobulin heavy chain-light chain pairs and uses thereof Chemistry; Metallurgy 10 Active
US7769573B2 System and method for modeling interactions Physics 9 Active
US10255409B2 Systems and methods for in silico evaluation of polymers Physics 8 Active
US9732155B2 Crystal structures of heterodimeric Fc domains Chemistry; Metallurgy 8 Active
US9988460B2 Crystal structures of heterodimeric Fc domains Chemistry; Metallurgy 8 Active
US9771573B2 Methods of quantitating heavy and light chain polypeptide pairs Chemistry; Metallurgy 7 Active
US9296815B2 Antibodies with enhanced or suppressed effector function Chemistry; Metallurgy 5 Active
US11161915B2 Antigen-binding polypeptide constructs comprising kappa and lambda light chains and uses thereof Chemistry; Metallurgy 4 Active
US10947319B2 Bispecific antigen-binding constructs targeting HER2 Chemistry; Metallurgy 4 Active
US11078296B2 Engineered immunoglobulin heavy chain-light chain pairs and uses thereof Chemistry; Metallurgy 3 Active
US11286293B2 Engineered immunoglobulin heavy chain-light chain pairs and uses thereof Chemistry; Metallurgy 3 Active
US11000598B2 Anti-HER2 biparatopic antibody-drug conjugates and methods of use Chemistry; Metallurgy 3 Active
US10457742B2 Stable heterodimeric antibody design with mutations in the Fc domain Chemistry; Metallurgy 3 Active
US10201614B2 Cytotoxic and anti-mitotic compounds, and methods of using the same Emerging Cross-Sectional Technologies 3 Active
US11306156B2 Modified antigen binding polypeptide constructs and uses thereof Chemistry; Metallurgy 3 Active
US10414822B2 Cytotoxic and anti-mitotic compounds, and methods of using the same Electricity 2 Active

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.