Patent · US Active

FXR (NR1H4) binding and activity modulating compounds

US10220027B2 · kind B2 · utility

9Cited by

21References

16Claims

0Family size

Assignee

Gilead Sciences, Inc. · US

Inventors

Olaf Kinzel · Heidelberg, DE
Christoph Steeneck · Dossenheim, DE
Claus Kremoser · Heidelberg, DE

Key dates

Filing date	Oct 13, 2017
Grant date	Mar 5, 2019
Priority date	—
Expiry date	Oct 13, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D413/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.