Patatin-like phospholipase domain containing 3 (PNPLA3) iRNA compositions and methods of use thereof
US10231988B2 · kind B2 · utility
6Cited by
2References
28Claims
0Family size
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Key dates
| Filing date | Aug 7, 2017 |
| Grant date | Mar 19, 2019 |
| Priority date | — |
| Expiry date | Aug 7, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/3515
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to RNAi agents, e.g., double stranded RNAi agents, targeting the Patatin-Like Phospholipase Domain Containing 3 (PNPLA3) gene, and methods of using such RNAi agents to inhibit expression of a PNPLA3 gene and methods of treating subjects having Nonalcoholic Fatty Liver Disease (NAFLD) and/or a PNPLA3-associated disorder.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.