Patent · US Active

Nontoxigenic Clostridium botulinum strains and uses thereof

US10253074B2 · kind B2 · utility

1Cited by

1References

11Claims

0Family size

Assignee

Wisconsin Alumni Research Foundation · US

Inventors

Eric A. Johnson · Hudson, US
Marite Bradshaw · Madison, US
Kristin M. Marshall · Madison, US

Key dates

Filing date	Aug 31, 2009
Grant date	Apr 9, 2019
Priority date	—
Expiry date	Jun 9, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N15/09
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A mutant strain of the bacterium Clostridium botulinum having an inactivated botulinal neurotoxin gene is disclosed. The mutant strain contains an artificially created and inserted modified intron vector between nucleotides 580 and 581 of the sense strand of the gene. The mutant strain can be used in microbiological challenge testing of foods and food processing methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.