Patent · US Active

Multiplex PCR to detect gene fusions

US10253349B2 · kind B2 · utility

0Cited by

0References

7Claims

0Family size

Assignee

Roche Molecular Systems, Inc. · US

Inventors

Ann Begovich · Corona, US
Rajiv Dua · Manteca, US
Dwight Kuo · Castro Valley, US
Xiaoju Max Ma · San Carlos, US
Ellen Ordinario · Oakland, US

Key dates

Filing date	Apr 15, 2016
Grant date	Apr 9, 2019
Priority date	—
Expiry date	Mar 31, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/686
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Provided herein are methods and compositions for detecting gene fusions, e.g., relevant to cancer. The present methods and compositions can be used to detect gene fusions with very high sensitivity and specificity. The present methods and compositions can detect gene fusions, e.g., in free circulating tumor RNA from a plasma sample.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.