Systems for biological sample processing and analysis

US10267790B1 · kind B1 · utility

Assignee

• Ultima Genomics, Inc. · US

Inventors

• Kristopher Barbee · East Haven, US
• Nathan Beckett · Oakland, US
• Denis Pristinski · Dublin, US
• Derek Schulte · Los Angeles, US
• Avishai Bartov · Hod HaSharon, IL
• Jamie M. Sullivan · Eugene, US
• Dumitru Brinza · Montara, US
• Abizar Lakdawalla · Los Altos Hills, US
• Steven M. Menchen · Fremont, US
• Gilad Almogy · Givatayim, IL
• Mark Pratt · Seattle, US

Key dates

• Filing date: May 8, 2018
• Grant date: Apr 23, 2019
• Expiry date: May 8, 2038

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/54366
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Provided are systems for biological sample processing and analysis. A system can comprise a substrate configured to rotate. The substrate can comprise an array configured to immobilize a biological analyte. A fluid flow unit comprising a fluid channel can be configured to dispense a solution comprising a plurality of probes. The solution may be directed, via centrifugal force, across the substrate during rotation of the substrate, to couple at least one of the plurality of probes with the biological analyte. A detector in optical communication with the array can be configured to detect one or more signals from the at least one probe coupled to the biological analyte.