Covalent inhibitors of kras G12C
US10273207B2 · kind B2 · utility
24Cited by
53References
34Claims
0Family size
Assignee
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Key dates
| Filing date | Feb 7, 2018 |
| Grant date | Apr 30, 2019 |
| Priority date | — |
| Expiry date | Feb 7, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/58
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Irreversible inhibitors of G12C mutant K-Ras protein are provided. Also disclosed are methods to modulate the activity of G12C mutant K-Ras protein and methods of treatment of disorders mediated by G12C mutant K-Ras protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.