Patent assignee · US · COMPANY

Araxes Pharma LLC

46Patents
46Active
46Granted
58Portfolio score

Filing activity: Mar 14, 2014 → Feb 14, 2023

Most-cited patents

PatentTitleAreaCited byStatus
US9840516B2 Substituted quinazolines as inhibitors of KRAS G12C Chemistry; Metallurgy 64 Active
US9227978B2 Covalent inhibitors of Kras G12C Physics 45 Active
US9745319B2 Irreversible covalent inhibitors of the GTPase K-Ras G12C Chemistry; Metallurgy 44 Active
US9810690B2 Method for screening inhibitors of Ras Physics 41 Active
US9862701B2 Inhibitors of KRAS G12C mutant proteins Chemistry; Metallurgy 39 Active
US9988357B2 Methods for preparation of quinazoline derivatives Chemistry; Metallurgy 38 Active
US9926267B2 Covalent inhibitors of K-Ras G12C Physics 37 Active
US10144724B2 Substituted quinazoline compounds and methods of use thereof Physics 36 Active
US10111874B2 Combination therapies for treatment of cancer Human Necessities 34 Active
US10414757B2 2-substituted quinazoline compounds comprising a substituted heterocyclic group and methods of use thereof Chemistry; Metallurgy 30 Active
US10370386B2 Substituted quinolines as inhibitors of KRAS G12C Chemistry; Metallurgy 29 Active
US10377743B2 Inhibitors of RAS and methods of use thereof Chemistry; Metallurgy 29 Active
US10246424B2 Substituted quinazoline compounds and methods of use thereof Chemistry; Metallurgy 27 Active
US10351550B2 Substituted quinazoline compounds and methods of use thereof Physics 27 Active
US10428064B2 Fused-tricyclic inhibitors of KRAS and methods of use thereof Chemistry; Metallurgy 27 Active
US10280172B2 Inhibitors of KRAS G12C mutant proteins Chemistry; Metallurgy 26 Active
US10736897B2 Compounds and methods of use thereof for treatment of cancer Chemistry; Metallurgy 26 Active
US10273207B2 Covalent inhibitors of kras G12C Physics 24 Active
US10646488B2 Conjugates of cereblon binding compounds and G12C mutant KRAS, HRAS or NRAS protein modulating compounds and methods of use thereof Human Necessities 18 Active
US10647703B2 Inhibitors of KRAS G12C mutant proteins Chemistry; Metallurgy 18 Active
US10689356B2 Inhibitors of KRAS G12C mutant proteins Chemistry; Metallurgy 16 Active
US10745385B2 Covalent inhibitors of KRAS Chemistry; Metallurgy 16 Active
US10730867B2 Inhibitors of KRAS G12C mutant proteins Human Necessities 15 Active
US10723738B2 Inhibitors of KRAS G12C mutant proteins Chemistry; Metallurgy 15 Active
US10829458B2 Substituted quinazoline compounds and methods of use thereof Chemistry; Metallurgy 12 Active

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.