Methods and systems for analyte detection and analysis

US10273528B1 · kind B1 · utility

Assignee

• Ultima Genomics, Inc. · US

Inventors

• Kristopher Barbee · East Haven, US
• Nathan Beckett · Oakland, US
• Denis Pristinski · Dublin, US
• Derek Schulte · Los Angeles, US
• Avishai Bartov · Hod HaSharon, IL
• Jamie M. Sullivan · Eugene, US
• Dumitru Brinza · Montara, US
• Abizar Lakdawalla · Los Altos Hills, US
• Steven M. Menchen · Fremont, US
• Gilad Almogy · Givatayim, IL
• Mark Pratt · Seattle, US

Key dates

• Filing date: May 8, 2018
• Grant date: Apr 30, 2019
• Expiry date: May 8, 2038

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/54366
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate configured to rotate. The open substrate can comprise an array of immobilized analytes. A solution comprising a plurality of probes may be directed, via centrifugal force, across the array during rotation of the substrate, to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via continuous rotational area scanning of the substrate.