Patent · US Active

Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

US10337010B2 · kind B2 · utility

12Cited by
5References
31Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 23, 2017
Grant dateJul 2, 2019
Priority date
Expiry dateAug 23, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2310/3515
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ANGPTL3 gene, as well as methods of inhibiting expression of ANGPTL3 and methods of treating subjects having a disorder of lipid metabolism, such as hyperlipidemia or hypertriglyceridemia, using such dsRNA compositions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.