Methods for biological sample processing and analysis

US10344328B2 · kind B2 · utility

Assignee

• Ultima Genomics, Inc. · US

Inventors

• Kristopher Barbee · East Haven, US
• Nathan Beckett · Oakland, US
• Denis Pristinski · Dublin, US
• Derek Schulte · Los Angeles, US
• Avishai Bartov · Hod HaSharon, IL
• Jamie M. Sullivan · Eugene, US
• Dumitru Brinza · Montara, US
• Abizar Lakdawalla · Los Altos Hills, US
• Steven M. Menchen · Fremont, US
• Gilad Almogy · Givatayim, IL
• Mark Pratt · Seattle, US

Key dates

• Filing date: May 8, 2018
• Grant date: Jul 9, 2019
• Expiry date: May 8, 2038

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/54366
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Provided are methods for biological sample processing and analysis. A method can comprise providing a substrate configured to rotate. The substrate can comprise an array having immobilized thereto a biological analyte. A solution comprising a plurality of probes may be directed, via centrifugal force, across the substrate during rotation of the substrate, to couple at least one of the plurality of probes with the biological analyte. A detector can be configured to detect a signal from the at least one probe coupled to the biological analyte, thereby analyzing the biological analyte.