Macrocyclic broad spectrum antibiotics
US10351595B2 · kind B2 · utility
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5References
19Claims
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Key dates
| Filing date | May 19, 2015 |
| Grant date | Jul 16, 2019 |
| Priority date | — |
| Expiry date | May 19, 2035 |
Classification
- Technology area (CPC —)General
Abstract
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.