Tricyclic compounds as inhibitors of mutant IDH enzymes
US10399972B2 · kind B2 · utility
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19Claims
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Inventors
Key dates
| Filing date | Oct 25, 2016 |
| Grant date | Sep 3, 2019 |
| Priority date | — |
| Expiry date | Oct 25, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to tricyclic compounds of formula (I), (Ia) or (Ib) which are inhibitors of one or more mutant IDH enzymes. The present invention is also directed to uses of these tricyclic compounds in the potential treatment or prevention of cancers in which one or more mutant IDH enzymes are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such cancers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.