Substituted nucleosides, nucleotides and analogs thereof

US10420788B2 · kind B2 · utility

Assignee

• ALIOS BIOPHARMA, INC. · US

Inventors

• Guangyi Wang · Carlsbad, US
• David Bernard Smith · San Mateo, US
• Leonid Beigelman · San Mateo, US
• Jerome Deval · Pacifica, US
• Marija Prhavc · Encinitas, US

Key dates

• Filing date: Jul 28, 2016
• Grant date: Sep 24, 2019
• Expiry date: Jul 28, 2036

Classification

• Technology area (CPC —): General

Abstract

Disclosed herein are nucleosides, nucleotides and analogs thereof, pharmaceutical compositions that include one or more of nucleosides, nucleotides and analogs thereof, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an infection from a paramyxovirus and/or an orthomyxovirus, with a nucleoside, a nucleotide and an analog thereof.