Cytotoxic and anti-mitotic compounds, and methods of using the same
US10450378B2 · kind B2 · utility
2Cited by
35References
61Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 17, 2015 |
| Grant date | Oct 22, 2019 |
| Priority date | — |
| Expiry date | Sep 17, 2035 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH10K59/1201
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds having cytotoxic and/or anti-mitotic activity are disclosed. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. Also disclosed are compositions having the structure: (T)-(L)-(D), wherein (T) is a targeting moiety, (L) is an optional linker, and (D) is a compound having cytotoxic and/or anti-mitotic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.