Humanized anti-Tau(pS422) antibodies and methods of use

US10465000B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Fiona Grueninger · Arlesheim, CH
• Guy Georges · Habach, DE
• Olaf Mundigl · Weilheim, DE
• Michael Schraeml · Penzberg, DE
• Bernd Bohrmann · Glückstadt, DE
• Ulrich Goepfert · Penzberg, DE
• Joerg Benz · Rheinfelden (Baden), DE
• Hubert Kettenberger · Munich, DE

Key dates

• Filing date: Dec 22, 2016
• Grant date: Nov 5, 2019
• Expiry date: Dec 22, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides humanized anti-human Tau(pS422) antibodies and methods of using the same.