Small molecule inhibitor of 3-phosphoglycerate dehydrogenase and uses thereof
US10494365B2 · kind B2 · utility
0Cited by
0References
21Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Dec 30, 2016 |
| Grant date | Dec 3, 2019 |
| Priority date | — |
| Expiry date | Dec 30, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Embodiments of the present invention are directed to small molecule inhibitors of PHGDH. Other embodiments of the present invention relate to methods of treating cancers using the small molecule inhibitors of PHGDH disclosed herein. Still other embodiments of the present invention relate to methods for using the small molecule inhibitors of PHGDH to study serine metabolism.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.