Insulin-like growth factor binding protein, acid labile subunit (IGFALS) compositions and methods of use thereof
US10494632B2 · kind B2 · utility
1Cited by
0References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 8, 2016 |
| Grant date | Dec 3, 2019 |
| Priority date | — |
| Expiry date | Jul 8, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/3515
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to RNAi agents, e.g., double stranded RNAi agents, targeting the insulin-like growth factor binding protein, acid labile subunit (IGFALS) gene or the insulin-like growth factor 1 (IGF-1) gene, methods of using such double stranded RNAi agents to inhibit expression of an IGFALS gene or an IGF-1 gene, and methods of treating subjects having an IGF system-associated disorder.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.