7-substituted 1-pyridyl-naphthyridine-3-carboxylic acid amides and use thereof

US10519154B2 · kind B2 · utility

Assignees

• Bayer Pharma Aktiengesellschaft · DE
• BAYER HEALTHCARE LLC · DE

Inventors

• Henrik Teller · Schwaan, DE
• Melissa BOULTADAKIS ARAPINIS · Düsseldorf, DE
• Alexandros Vakalopoulos · Hilden, DE
• Anne-Sophie REBSTOCK · Écully, FR
• Alexander Straub · Wuppertal, DE
• Hanna Tinel · Wuppertal, DE
• Markus BRECHMANN · Marburg, DE
• Matthias Beat WITTWER · Riehen, CH
• Maximillian Andreas Kullmann · Leichlingen, DE
• Klaus Münter · Mannheim, DE
• Thomas MONDRITZKI · Essen, DE
• Tobias Marquardt · Wuppertal, DE

Key dates

• Filing date: Jul 4, 2017
• Grant date: Dec 31, 2019
• Expiry date: Jul 4, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to novel 7-substituted 1-pyridylnaphthyridine-3-carboxamides, to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prevention of diseases, and to their use for the production of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders and/or renal disorders.