Peptidomimetic compounds and antibody-drug conjugates thereof

US10533058B2 · kind B2 · utility

Assignees

• Genentech, Inc. · US
• MedImmune Limited · US

Inventors

• John A. Flygare · Burlingame, US
• Janet Gunzner-Toste · South San Francisco, US
• Thomas Pillow · South San Francisco, US
• Brian Safina · South San Francisco, US
• Vishal Verma · San Francisco, US
• BinQing Wei · Belmont, US
• Guiling Zhao · South San Francisco, US
• Leanna Staben · San Francisco, US
• Philip Wilson Howard · London, GB
• Luke Masterson · Cambridge, GB

Key dates

• Filing date: Dec 16, 2014
• Grant date: Jan 14, 2020
• Expiry date: Mar 5, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/56
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to peptidomimetic linkers and anti-body drug conjugates thereof, pharmaceutical compositions containing them, and to their use in therapy for the prevention treatment of cancer.