Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof
US10570393B2 · kind B2 · utility
12Cited by
5References
46Claims
0Family size
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Key dates
| Filing date | Oct 12, 2017 |
| Grant date | Feb 25, 2020 |
| Priority date | — |
| Expiry date | Oct 12, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/51
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ANGPTL3 gene, as well as methods of inhibiting expression of ANGPTL3 and methods of treating subjects having a disorder of lipid metabolism, such as hyperlipidemia or hypertriglyceridemia, using such dsRNA compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.