Patent · US Active

Fc variants with increased affinity for FcγRIIc

US10584176B2 · kind B2 · utility

9Cited by

63References

10Claims

0Family size

Assignee

Xencor, Inc. · US

Inventors

Gregory Alan Lazar · Los Angeles, US
Wei Dang · Pasadena, US
John Desjarlais · Pasadena, US
Sher Bahadur Karki · Pasadena, US
Omid Vafa · Monrovia, US
Robert Hayes · Paoli, US

Key dates

Filing date	Sep 21, 2018
Grant date	Mar 10, 2020
Priority date	—
Expiry date	Sep 21, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/94
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to Fc variants having increased affinity for FcγRIIc, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.