Patent assignee · US · COMPANY

Xencor, Inc.

🏢 View company profile →
215Patents
191Active
215Granted
55Portfolio score

Filing activity: Oct 15, 1999 → Aug 20, 2024 · 39 expiring within 5 years

Most-cited patents

PatentTitleAreaCited byStatus
US7317091B2 Optimized Fc variants Chemistry; Metallurgy 439 Expired
US7662925B2 Optimized Fc variants and methods for their generation Chemistry; Metallurgy 205 Active
US8367805B2 Fc variants with altered binding to FcRn Emerging Cross-Sectional Technologies 171 Active
US8188231B2 Optimized FC variants Chemistry; Metallurgy 161 Active
US7276585B2 Immunoglobulin variants outside the Fc region Chemistry; Metallurgy 148 Expired
US6403312B1 Protein design automatic for protein libraries Chemistry; Metallurgy 139 Expired
US8637641B2 Antibodies with modified isoelectric points Chemistry; Metallurgy 124 Active
US7315786B2 Protein design automation for protein libraries Physics 119 Expired
US8063187B2 Methods and compositions for inhibiting CD32B expressing cells Chemistry; Metallurgy 109 Active
US8101720B2 Immunoglobulin insertions, deletions and substitutions Chemistry; Metallurgy 92 Active
US7657380B2 Methods of generating variant antibodies with increased host string content Physics 85 Expired
US8084582B2 Optimized anti-CD20 monoclonal antibodies having Fc variants Chemistry; Metallurgy 76 Active
US8088376B2 Fc variants with altered binding to FcRn Emerging Cross-Sectional Technologies 72 Active
US6514729B1 Recombinant interferon-beta muteins Human Necessities 69 Expired
US8802820B2 Fc variants with altered binding to FcRn Chemistry; Metallurgy 68 Active
US9856327B2 Heterodimeric antibodies to CD3 X CD123 Chemistry; Metallurgy 64 Active
US8039592B2 Optimized Fc variants and methods for their generation Physics 57 Active
US8388955B2 Fc variants Chemistry; Metallurgy 53 Active
US8329867B2 CTLA4-Ig immunoadhesins Chemistry; Metallurgy 53 Active
US8124731B2 Optimized Fc variants and methods for their generation Chemistry; Metallurgy 50 Active
US8735545B2 Fc variants having increased affinity for fcyrllc Chemistry; Metallurgy 37 Active
US8093359B2 Optimized Fc variants and methods for their generation Physics 36 Active
US7056695B2 TNF-α variants Human Necessities 35 Expired
US9605061B2 Antibodies with modified isoelectric points Chemistry; Metallurgy 35 Active
US8093357B2 Optimized Fc variants and methods for their generation Chemistry; Metallurgy 34 Active

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.