Patent · US Active

Polymerase variants

US10612009B2 · kind B2 · utility

0Cited by

2References

7Claims

0Family size

Assignees

Roche Sequencing Solutions, Inc. · US
Roche Molecular Systems, Inc. · US

Inventors

Aruna Ayer · Santa Clara, US
Cleoma Arnold · San Jose, US
Arkadiusz Bibillo · Cupertino, US
Mara Boenitz-Dulat · Tutzing, DE
Barbara Eckert · Corona, US
Ilya Lederman · San Francisco, US
Colin Alexander McGaw · Santa Clara, US
Charles Wayan Schwab · San Ramon, US
Tyler O'Brien Shultz · Santa Clara, US
Shawn Suko · El Sobrante, US
Eileen Thai · San Jose, US
Bigna Woersdoerfer · Munich, DE
David Daniel Wunderlich · Penzberg, DE

Key dates

Filing date	Apr 29, 2019
Grant date	Apr 7, 2020
Priority date	—
Expiry date	Apr 29, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y207/07007
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Described herein is a variant pol6 polymerase having at least one mutation selected from H223, N224, Y225, H227, I295, Y342, T343, I357, S360, L361, I363, S365Q, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, Q546, A547, L549, I550, N552, G553, F558, A596, G603, A610, V615, Y622, C623, D624, I628, Y629, R632, N635, M641, A643, 1644, T647, I648, T651, I652, K655, W656, D657, V658, H660, F662, L690 and combinations thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.