HER3 antigen binding proteins binding to the beta-hairpin of HER3

US10626177B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Birgit Bossenmaier · Hanerau-Hademarschen, DE
• David Casagolda Vallribera · Penzberg, DE
• Guy Georges · Habach, DE
• Michael Gerg · Munich, DE
• Gerhard Niederfellner · Oberhausen, DE
• Christian Scholz · Penzberg, DE
• Michael Schraeml · Penzberg, DE

Key dates

• Filing date: Aug 3, 2017
• Grant date: Apr 21, 2020
• Expiry date: Aug 3, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/70
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to anti-HER3 antigen binding proteins, e.g. anti-HER3 antibodies, that bind to the beta-hairpin of HER3, methods for selecting these antigen binding proteins, their preparation and use as medicament.