Dopamine D2 receptor ligands
US10633336B2 · kind B2 · utility
2Cited by
19References
22Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Dec 18, 2015 |
| Grant date | Apr 28, 2020 |
| Priority date | — |
| Expiry date | Dec 18, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/70571
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders associated with dysregulation of dopaminergic activity. The present invention relates to novel compounds that modulate dopamine D2 receptors. In particular, compounds of the present invention show functional selectivity at the dopamine D2 receptors and exhibit selectivity downstream of the D2 receptors, on the 0-arrestin pathway and/or on the cAMP pathway.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.