Patent · US Active

Heterocycle-substituted tetracyclic compounds and methods of use thereof for the treatment of viral diseases

US10646494B2 · kind B2 · utility

0Cited by

2References

16Claims

0Family size

Assignee

Merck Sharp & Dohme LLC · US

Inventors

Wensheng Yu · Edison, US
Ling Tong · Hackettstown, US
Joseph A. Kozlowski · Princeton, US
Craig A. Coburn · Royersford, US
De-Yi Yang · Morristown, US
Deyou Sha · Yardley, US
Jae-Hun Kim · Scotch Plains, US
Michael P. Dwyer · Scotch Plains, US
Kartik M. Keertikar · Plainsboro, US
Bin Hu · Mesa, US
Bin Zhong · Shanghai, CN
Jinglai Hao · Shanghai, CN
Dahai Wang · Shanghai, CN

Key dates

Filing date	Aug 14, 2017
Grant date	May 12, 2020
Priority date	—
Expiry date	Aug 14, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D519/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to novel Heterocycle-Substituted Tetracyclic Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, A′, R2 R3 and R5 are as defined herein. The present invention also relates to compositions comprising at least one Heterocycle-Substituted Tetracyclic Compound, and methods of using the Heterocycle-Substituted Tetracyclic Compounds for treating or preventing HCV infection in a patient.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.