Illumination microscopy systems and methods

US10656403B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Secretary, Department of Health and Human Services · US

Inventors

• Hari Shroff · Rockville, US
• Andrew York · Bethesda, US

Key dates

• Filing date: Apr 18, 2019
• Grant date: May 19, 2020
• Expiry date: Apr 18, 2039

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2201/0633
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A structured illumination microscopy (SIM) system for generating single focal point patterns of a sample is disclosed. The SIM system performs a focusing, scaling and summing operation on each single focal point that completely scan the sample to produce a high resolution composite image.