Patent · US Active

Backbone cyclized inhibitory peptides of myeloid differentiation factor 88 (MyD88)

US10662225B2 · kind B2 · utility

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9References

9Claims

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Assignee

YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. · IL

Inventors

Gabriel Nussbaum · Jerusalem, IL
Amnon Hoffman · Jerusalem, IL
Chaim Gilon · Jerusalem, IL

Key dates

Filing date	Jun 4, 2017
Grant date	May 26, 2020
Priority date	—
Expiry date	Jun 4, 2037

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided are backbone cyclized peptides that interfere with signaling of the intracellular adaptor protein MyD88. Pharmaceutical compositions including these backbone cyclized peptides as well as their use in treatment of multiple sclerosis (MS) and other diseases associated with MyD88 signaling are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.