Patent · US Active

Methods and compositions for the specific inhibition of transthyretin (TTR) by double-stranded RNA

US10676742B2 · kind B2 · utility

1Cited by

14References

30Claims

0Family size

Assignee

Dicerna Pharmaceuticals, Inc. · US

Inventors

Bob D. Brown · Littleton, US
Henryk T. Dudek · Wellesley, US

Key dates

Filing date	Oct 23, 2018
Grant date	Jun 9, 2020
Priority date	—
Expiry date	Oct 23, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/178
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention relates to compounds, compositions, and methods useful for reducing transth:yretin (TTR) target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate siRNA (DsiRNA) agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.