Patent · US Active

Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors

US10683298B2 · kind B2 · utility

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22References
8Claims
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Key dates

Filing dateNov 12, 2018
Grant dateJun 16, 2020
Priority date—
Expiry dateNov 12, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D498/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein are Heteroaryl Compounds having the following structure: Further provided herein are methods for the preparation of substituted pyrazino[2,3-b]pyrazines of formula (II): the method comprising contacting a compound of formula (VI): the method further comprising cyclizing a compound of formula (VII)

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.