Aminopyrazine compounds with A2A antagonist properties
US10688082B2 · kind B2 · utility
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Key dates
| Filing date | Jun 6, 2016 |
| Grant date | Jun 23, 2020 |
| Priority date | — |
| Expiry date | Jun 6, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are compounds having the structure of Formula I, or a pharmaceutically acceptable salt of any thereof, wherein: “Z”, R1 and R2 are defined herein, which compounds are believed suitable for use in selectively antagonizing the A2a receptors, for example, those found in high density in the basal ganglia. Such compounds and pharmaceutical formulations are believed to be useful in treatment or management of neurodegenerative diseases, for example, Parkinson's disease, or movement disorders arising from use of certain medications used in the treatment or management of Parkinson's disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.