Ultrapurified DsbA and DsbC and methods of making and using the same
US10690671B2 · kind B2 · utility
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46Claims
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Key dates
| Filing date | Jul 24, 2018 |
| Grant date | Jun 23, 2020 |
| Priority date | — |
| Expiry date | Jul 24, 2038 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods for producing disulfide oxidoreductase A (DsbA) and disulfide oxidoreductase C (DsbC) polypeptides at very high levels of purity. Also provided are ultrapure DsbA and DsbC and methods of using same, e.g., for use in immunoassays to show removal of DsbA and DsbC from biologics produced in bacteria.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.