Shape memory particles for biomedical uses
US10695427B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Apr 6, 2016 |
| Grant date | Jun 30, 2020 |
| Priority date | — |
| Expiry date | Apr 6, 2036 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The presently disclosed subject matter provides compositions, methods, and kits comprising shape memory particles that can be used for delivering a drug and/or treating a disease or disorder in a patient. Specifically, shape changes in the presently disclosed shape memory particles can be used to control drug delivery spatially and/or temporally in a patient. Also provided are compositions, methods, and kits comprising nanoparticles and hypoxia-inducible factor (HIF) inhibitors with or without chemotherapeutic agents for inhibiting HIF activity in a patient and/or treating a hypoxia-associated disease or disorder.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.