Biosensor for optical detection of nucleotide sequence
US10718758B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 3, 2016 |
| Grant date | Jul 21, 2020 |
| Priority date | — |
| Expiry date | Feb 22, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5438
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates generally to the field of microelectronics, and more particularly to a structure and method of forming a biosensor having a nucleotide attracting surface tailored to reduce false detection of nucleotides and enabling optical detection of nucleotides. The biosensor may include an analyte-affinity layer on an upper surface of a dielectric layer. The analyte-affinity layer may include a plurality of cylindrical gold portions with dimensions tailored for a target analyte. A distance between adjacent portions of the plurality of portions may range from approximately 50% of a length of a target analyte to approximately 300% of a length of a target analyte. The plurality of portions of the analyte-affinity layer have an upper surface with a diameter ranging from approximately 3 nm to approximately 20 nm.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.