Bispecific antibodies and methods of use in ophthalmology

US10730938B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Marc Bedoucha · Ranspach-le-Haut, FR
• Sebastian Breuer · Penzberg, DE
• Stefan Dengl · Munich, DE
• Christian Gassner · Penzberg, DE
• Guy Georges · Habach, DE
• Sabine Gruener · Weil am Rhein, DE
• Guido Hartmann · Soest, DE
• Peter Michael Huelsmann · Habach, DE
• Hubert Kettenberger · Munich, DE
• Joerg Moelleken · Penzberg, DE
• Michael Molhoj · Munich, DE
• Olaf Mundigl · Weilheim, DE
• Joerg Thomas Regula · Munich, DE
• Ralf Schumacher · Penzberg, DE
• Barbara Weiser · East Greenbush, US

Key dates

• Filing date: May 9, 2017
• Grant date: Aug 4, 2020
• Expiry date: May 9, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/94
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Herein are reported novel bispecific antibodies that specifically bind to two different antigens selected from the group consisting of human ANG2, human VEGF, human IL-1beta and human PDGF-B.