Methods and devices for the production of decellularised tissue scaffolds
US10792395B2 · kind B2 · utility
3Cited by
1References
32Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 29, 2016 |
| Grant date | Oct 6, 2020 |
| Priority date | — |
| Expiry date | Jan 11, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2527/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to a method of producing a decellularised tissue scaffold which comprising treating a sample of tissue with an osmotic reagent and a detergent whilst subjecting the tissue sample to oscillation with a displacement of 1 mm or more and a frequency of 3 Hz or more during these treatment steps. This method may be useful in producing acellular scaffolds that maintain the 3-D architecture and extracellular matrix composition and morphology of the native tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.