Patent · US Active

Broad range gene and genotype papillomavirus transcriptome as a biomarker of papillomavirus-associated cancer stages

US10808284B2 · kind B2 · utility

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16Claims

0Family size

Assignees

INSTITUT PASTEUR · FR
ECOLE NATIONALE VETERINAIRE D'ALFORT · FR
PATHQUEST · FR
L'ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS · FR

Inventors

Marc Eloit · Paris, FR
Nicolas TORNO · Paris, FR
Jean Deregnaucourt · Paris, FR
Marion Mouton · Paris, FR
Isabelle Heard · Paris, FR
Philippe Perot · L'Essart Mador, FR

Key dates

Filing date	Jul 7, 2015
Grant date	Oct 20, 2020
Priority date	—
Expiry date	Jul 7, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/16
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention provides compositions, kits, and method for determining the levels of expression of human polyoma or papillomavirus species and RNA transcripts. These levels can be used for the prognosis of risk of developing virally-induced cancers. The ratio (R) between early and late transcripts is indicative of HPV infections associated with higher risk of developing genital neoplasia and cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.