Patent · US Active

Feed mixing device and its use

US10837042B2 · kind B2 · utility

0Cited by

6References

8Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Sylvia Baumann · Penzberg, DE
Jens Hoffmann · Mühlenbeck, DE
Alexander Jockwer · Eurasburg, DE
Christian Klinger · Penzberg, DE
Thomas Troebs · Munich, DE

Key dates

Filing date	Sep 22, 2017
Grant date	Nov 17, 2020
Priority date	—
Expiry date	Oct 30, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2500/60
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Herein is reported a feed mixing device for adding feed solutions with a non-physiologically pH value to a cell cultivation vessel comprising a chamber for mixing the feed solutions prior to their addition to the cell cultivation vessel as well as its use. With the feed mixing device as reported herein feed components can be provided in solution at a pH value at which they have good solubility and/or good stability whereby the pH value can be clearly different from the pH value of the cultivation medium, i.e. different from the physiological pH value. This allows performing the cultivation with more flexibility compared to a cultivation in which the pH value of the feed solution is limited to a small range around the pH value of the cultivation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.