Methods and compositions for natural killer cells
US10874715B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Sep 21, 2018 |
| Grant date | Dec 29, 2020 |
| Priority date | — |
| Expiry date | Sep 30, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/599
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The application provides new compositions and methods for stimulating the production of natural killer (NK) cells in a subject. NK cells can be selectively expanded with a combination of stimulating ligands. Methods and compositions for the administration of stimulatory ligands modified to self-insert into tumor cells, thereby stimulating an increase in the number of NK cells in proximity to a tumor, are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.