Patent · US Active

Host cell comprising nucleic acids encoding bispecific antibodies binding to beta-klotho and fibroblast growth factor receptor 1 and antibody production

US10882921B2 · kind B2 · utility

0Cited by

21References

21Claims

0Family size

Assignee

Genentech, Inc. · US

Inventors

Yongmei Chen · 丈亭镇, CN
James Ernst · San Francisco, US
Hok Seon Kim · South San Francisco, US
Junichiro Sonoda · South San Francisco, US
Christoph Spiess · South San Francisco, US
Scott Stawicki · South San Francisco, US
Yan Wu · Foster City, US

Key dates

Filing date	Feb 25, 2019
Grant date	Jan 5, 2021
Priority date	—
Expiry date	Jul 6, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.