Preparation and uses of pyrimidinone derivatives
US10919896B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Sep 22, 2017 |
| Grant date | Feb 16, 2021 |
| Priority date | — |
| Expiry date | Sep 22, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compounds of formula (I), and salts and solvates thereof, that function as inhibitors of cell division cycle 7 (Cdc7) kinase enzyme activity: wherein X, R1, R2, and n are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which Cdc7 kinase activity is implicated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.